Introduction
The use of genomics across the cancer continuum is expanding rapidly, with broad implications for cancer control, including patient care, service delivery, workforce, research and data, and policy.
Methods
Cancer Australia developed the Australian Cancer Plan with extensive consultation across the sector, to determine a 10-year reform agenda to improve experience and outcomes for all Australians affected by cancer. Public submissions highlighted equitable access to genomics in cancer control as a key priority. A desktop review of national and international general and cancer-specific genomics policy frameworks identified an evidence gap in national cancer-specific genomic policy. A multidisciplinary expert advisory group was established to guide the development of a National Framework for Genomics in Cancer Control for Australia.
Results
Development of the Framework has commenced as an early implementation priority of the Australian Cancer Plan. Two key areas have emerged as critical for the Framework: the role of genetic testing in prevention, risk-stratified screening and early detection of cancer; and the use of genomics to inform clinical trials, personalised treatments and supportive care for cancer, in particularly for advanced and rare cancers. The Framework development process will adopt a co-design approach with Aboriginal and Torres Strait Islander communities to ensure that it is culturally appropriate and includes consideration of Indigenous Data Sovereignty.
Conclusions
An important opportunity exists to improve equitable cancer outcomes in Australia via a National Framework for Genomics in Cancer Control. The Framework will be for consumers, health professionals, policymakers, researchers, governments, non-government organisations, industry and the community. It will establish approaches to determining who, how and when people at risk of, and with cancer, will have access to genomics, with a focus on mitigating the risk of broadening disparities in care and outcomes.