Poster Presentation Clinical Oncology Society of Australia Annual Scientific Meeting 2023

Comparative Analysis of Survival Outcomes and Prognostic Significance of Brain Metastasis in Lung Cancer Patients across Gippsland   (#234)

Bhavini Shah 1 , Bridget Josephs 1 , Mahesh Iddawela 1 , Hieu Chau 1 , Evangeline Samuel 1 , Cassandra Moore 1 , Sophie Tran 1 , Danielle Roscoe 1
  1. Latrobe Regional Health, Traralgon, VIC, Australia

This study presents a comprehensive analysis of survival outcomes and prognostic implications associated with brain metastasis in lung cancer patients across the Gippsland region. The primary objective of this research is to compare the survival rates of patients diagnosed with lung cancer accompanied by brain metastasis to those with metastatic lung cancer alone. Additionally, the study evaluates brain metastasis as an independent predictor of mortality and morbidity in lung cancer patients across Gippsland.

Utilizing retrospective data between January 2017 to December 2022, the study examines clinical records of 101 patients from Latrobe Regional Hospital in Gippsland. Statistical analyses were conducted to assess differences in survival rates between patients with and without brain metastasis, accounting for various demographic and clinical variables. Furthermore, the research investigates the relationship between brain metastasis and its impact on overall patient outcomes, considering factors such as treatment modalities, disease stage, and comorbidities.

The findings of this study reveal significant disparities in survival rates between patients with lung cancer and brain metastasis compared to those without brain involvement. The implications of these findings are crucial for oncologists, healthcare providers, and policymakers in refining treatment strategies, enhancing patient care, and allocating resources effectively.

In conclusion, this study underscores the importance of recognizing brain metastasis as a pivotal factor influencing the survival and prognosis of lung cancer patients in the Gippsland region. By elucidating the distinct survival outcomes in patients with and without brain metastasis, and by establishing brain metastasis as an independent predictor of mortality and morbidity, this research contributes valuable insights to the field of oncology. Ultimately, these insights have the potential to drive improvements in clinical decision-making and patient outcomes across various cancer types in Gippsland and beyond.