Our research team is focused on moving data to evidence and impact with novel analytics and visualizations. The presentation will highlight several of the data-driven research initiatives underway to advance cancer prevention and screening efforts in Canada. Our team has been actively engaged in epidemiologic studies of risk factors for common cancers. As part of the translation of this work, we completed Canadian Population Attributable Risk of Cancer (ComPARe) Project. The ComPARe project was a comprehensive research effort to estimate the population-level cancer burden related to all known modifiable (lifestyle, infectious, environmental) exposures in Canada. An impactful knowledge mobilization campaign followed the completion of the research with many of the knowledge products now available online https://prevent.cancer.ca. As a follow-up to this work, we have also integrated our estimates into a microsimulation framework that can estimate the costs associated with risk-factor associated cancers and may present as a framework to evaluate the cost-effectiveness of future prevention activities/programs. The presentation will highlight the national collaborations and frameworks that were essential to complete this work. These efforts have now been included in provincial and national cancer control strategy documents that are focused on mitigating the impact of cancer, and amplifying awareness in cancer prevention and screening. The presentation will also detail efforts to employ novel data visualizations through digital data dashboards, communication tools, and knowledge translation strategies to fast-track the journey from research data to evidence and impact.